Dr. Judith Shizuru

Professor, Department of Medicine - Med/Blood and Marrow Transplantation, Stanford University

Research

Her research aims to improve the safety and efficacy of hematopoietic cell transplantation (HCT), the most widely practiced and powerful form of cellular therapy. Her work addresses two fundamental issues of HCT – preparation of recipients to permit hematopoietic stem cell (HSC) to engraft, and the impact of the graft cellular content on the success of the therapy, including solid organ replacement. Dr. Shizuru is a practicing physician-scientist who is overseeing clinical trials using hematopoietic stem cell transplantation‐based strategies for treating immunodeficiency and autoimmunity. She has previously collaborated with members of the BMT division including Drs. Meyer and Strober in exploring mixed‐chimerism‐based approaches to promote allotolerance in solid organ transplantation. She is working with Drs. Meyer, Kim and others at Stanford Diabetes Research Center to establish an islet transplant program at Stanford which should enable allotolerance trials focused on islet transplantation in type 1 and type 2 diabetes. She will serve as co‐PI on Projects 1 and 2 and also co‐direct Core B.