JDRF Northern California Center of Excellence

Stanford and UCSF

Covid-19 information

Our Mission

Center of Excellence: A center of excellence (COE) brings together people from different disciplines and provides shared facilities/resources

JDRF Centers of Excellence are intended to support Universities and/or Research Institutes that have a track record of excellence in T1D research to develop and pursue collaborative research programs that drive towards translational outcomes and clinical impact and are aligned with JDRF Research goals.

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Faculty Profile: Kyle Loh, PhD

Professor and the Anthony DiGenova Endowed Faculty Scholar, , Stanford University

Type 1 Diabetes in an autoimmune disease. Therefore, the ability to efficiently generate human immune cell-types in vitro, and to engineer them with desired combinations of mutations, could be used to eventually understand and treat Type 1 Diabetes. To this end, the Loh group seeks to reconstitute the development of human blood-forming hematopoietic stem cells (HSCs) and T cells in vitro from human pluripotent stem cells (hPSCs). Advances by the Loh Laboratory have led to strategies for efficiently generating primitive streak, endoderm and foregut precursors from hPSCs.

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