Assistant Professor, Medicine - Med/Blood and Marrow Transplantation, Stanford University
Dr. Meyer has a focus on the study of human immune tolerance in the hematopoietic stem cell setting and islet cell transplantation. He studies murine pre-clinical models with a focus on T cell immunotherapy, T regulatory cell and invariant NKT cell biology and non-myeloblative hematopoietic stem cell transplantation for tolerance induction. In established collaborations with Dr. Seung Kim, Dr. Meyer has developed genetic engineering to reprogram Tregulatory cells to target them to mouse islet allografts and human islet xenografts. This approach has resulted in some startling discoveries: (1) genetically engineered Tregulatory cells producing Chimeric Antigen Receptor (CAR) are much better at preventing islet graft rejection than normal Tregulatory cells and (2) genetically engineered Tregulatory cells can alter the immune system to create new immune memory and tolerance.